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How Many Xanax Does It Take to Overdose

When does Xanax overdose occur? It takes place when the pills are consumed in doses higher than prescribed either intentionally or accidentally. As for today, Xanax (Alprazolam) is a widely abused medication, which is why it is also a controlled drug that is not allowed to be consumed without prescription. It affects the brain’s neurotransmitters and produces calming effects, when taken as prescribed. But how many Xanax to overdose is taken? Knowing the overdose amount is essential to avoid possible complications.

How to Know You Suffer from Overdose?

There are basic Xanax OD symptoms that are the first signs of something going wrong. Here are the basic ones:

  • Drowsiness;
  • Confusion;
  • General clumsiness;
  • Breathing difficulties;
  • Loss of balance.

When the medication is combined with strong drinks or any other potent drugs, OD becomes fatal to the affected patient. Why combining Alprazolam with alcohol poses so many dangers? The matter is that both substances are powerful depressants. If used together, they grow in efficacy and a person runs the risk of a serious condition like respiratory depression and heart stoppage, coma and even death. When the very first breathing difficulties are experienced, please call 911.

How Many Xanax Does It Take to Overdose?

There is no one clear answer to how much Xanax to overdose. Why not? The amount of medication required for overdose depends on one’s previous exposure to Xanax, body weight and medical history. But what amount should be administered at a time? It is not recommended to take above 2 mg at one time. How many Xanax to OD? Around 2.5 mg will surely lead to first overdose symptoms. Even when someone has already developed tolerance to 2 mg pills, taking more is still not suggested.

At times it is enough to take a low dose to suffer from severe consequences. How so? The matter is that OD cases can occur when low doses are combined with alcohol or other opiates.

The medication can even cause coma and death, when a patient takes more than prescribed. If you are prescribed 0.25-0.5 mg doses, administering 1.0 mg pills can have dangerous adverse reactions.

As we have already mentioned, cases of Xanax abuse aren’t rare either. There are users, who report taking around 2000 mg of Xanax daily and they still experience minor toxicity. Note that a dose that is 1000 time higher than the normal one is incredibly dangerous and causes death.

What Are Lethal Doses?

Many researches were conducted as to the amount of the so-called lethal dose of Xanax. It is a proven fact that 331-2.171 mg of the drug per 1 kilogram of patient’s weight is the dosage that is referred as a lethal one. What does it all mean? When a person takes an extremely high Alprazolam dose like this to reach the greatest therapeutic effect or just the ‘high’ level, the level of toxicity gets really extreme and a person dies. And though Xanax is regarded as a relatively safe medication, it remains safe only when taken according to doctor’s prescription.

How many Xanax will kill you and what other factors demine the lethal dosage? The British Journal of Clinical Pharmacology has published the results on another study that proves Alprazolam to be more toxic than any other medications from the benzodiazepine group. Aside from such basic factors like age, weight and health state that can influence the results, there are some other personal factors.

How to Treat Xanax Overdose Cases?

Can Xanax kill you? Most patients truly believe that this outcome is next to impossible. Yet when the overdose condition is left untreated, it may lead to coma and even death. That’s why it is highly essential to get immediate medical help, when the first OD symptoms appear.

The first thing to be done is to call 911, no matter whether the symptoms are minor and severe. It is essential to inform a healthcare provider how much was taken. An affected person should be treated in a hospital. No home remedy is effective enough to provide the needed help. A sufferer is normally closely monitored to ensure that he doesn’t go into distress. Patients with low blood pressure and hypotension are paid special attention to.

In case Alprazolam is administered recently, you may need to have the stomach pumped in order to remove the medication. It is advisable to take Flumazenil. This is an antidote for benzodiazepine OD cases. When Flumazenil is administered, the patient is carefully monitored for re-sedation and respiratory depression.

Alternative medications and fluids may be prescribed to ensure relief and the absence of long-term adverse reactions. Though the severest symptoms can be quickly relieved even in cases of Xanax lethal dose, the process of moving into recovery may be pretty durable.

Now that you know how much Xanax does it take to overdose, be very careful when administering the drug. Don’t be shy to ask your doctor more questions on use and possible complications, overdose symptoms and their relief. Any information will be helpful while on Alprazolam.

Dr. Andrew J. Olson

Author: Dr. Andrew J. Olson

Dr. Andrew J. Olson is a PHD in psychiatry. He is also a psychiatrist consultant at the Royal Berkshire NHS Foundation Trust. He also serves as a Clinical Director of the Department of Psychiatry, at Royal Marsden Hospital, in London, UK.


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When does Xanax overdose occur? It takes place when the pills are consumed in doses higher than prescribed either intentionally or accidentally. As for today, Xanax (Alprazolam) is a widely abused medication, which is why it is also a controlled drug that is not allowed to be consumed without prescription. It affects the brain’s neurotransmitters and produces calming effects, when taken as prescribed. But how many Xanax to overdose is taken? Knowing the overdose amount is essential to avoid possible complications. How to Know You Suffer from Overdose? There are basic Xanax OD symptoms that are the first signs of…
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